Growth Hormone 1 anticorps (AA 58-187) (CF®488A)

N° du produit ABIN6163621

L’anticorps Souris Monoclonal anti-Growth Hormone 1 a été validé pour IHC, IF et FACS. Il convient pour détecter Growth Hormone 1 dans des échantillons de Humain.

Aperçu rapide pour Growth Hormone 1 anticorps (AA 58-187) (CF®488A) (ABIN6163621)

Antigène: Growth Hormone 1 (GH1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Growth Hormone 1 est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: GH-1371

Détail du produit anti-Growth Hormone 1 anticorps (CF®488A)

Épitope: AA 58-187

Fonction: Mouse Monoclonal anti-Growth Hormone (GH/1371), CF488A Conjugate

Attributs du produit: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: A recombinant human Growth Hormone (GH) fragment (aa58-187) (exact sequence is proprietary)

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistology (formalin) 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Pituitary cells or Pituitary

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur Growth Hormone 1

Antigène: Growth Hormone 1 (GH1)

Autre désignation: Growth Hormone

Sujet: GH, GH-N, GH1, GHN, Growth hormone 1, Growth hormone, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin

Poids moléculaire: 20 kDa

ID gène: 2688, 655229

UniProt: P01241

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process